�Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced that following U.S. Food and Drug Administration (FDA) review, the Company is initiating a U.S. Phase 2 clinical test using endovenous administration of REOLYSIN(R) in combination with paclitaxel and carboplatin in patients with non-small cell lung cancer (NSCLC) with K-RAS or EGFR-activated tumours. The Principal Investigator is Dr. Miguel Villalona-Calero, Professor Division of Hematology/Oncology and Department of Internal Medicine and Pharmacology at The Ohio State University Comprehensive Cancer Center.
"In this era of personalized malignant neoplastic disease treatment, we are quite a excited about this trial," said Dr. Villalona-Calero. "Although we hold had for some time treatments that target EGFR, K-RAS has been an elusive target. REOLYSIN(R) has the potency to objective K-RAS activated tumors, possibly enhancing the beneficial effects produced by chemotherapy."
"This trial gives Oncolytics the opportunity to treat NSCLC patients in a first-line clinical scope," said Dr. Brad Thompson, President and CEO of Oncolytics. "Assuming we achieve an satisfactory response pace, the combination of REOLYSIN(R) with paclitaxel and carboplatin for NSCLC would be a strong candidate for registration studies."
This trial is a single arm, two-stage, open-label, Phase 2 study of REOLYSIN(R) granted intravenously with paclitaxel and carboplatin every 3 weeks. Patients will receive quartet to six cycles of paclitaxel and carboplatin in conjunction with REOLYSIN(R), at which meter REOLYSIN(R) may be continued as a monotherapy. It is hoped-for that up to 36 patients will be tempered in this trial.
Eligible patients include those with metastatic or recurrent NSCLC with K-RAS or EGFR-activated tumours, wHO have non received chemotherapy treatment for their metastatic or recurrent disease. Patients must get demonstrated mutations in K-RAS or EGFR, or EGFR gene amplification in their tumours (metastatic or primary) in parliamentary procedure to condition for the trial.
The primary objectives of the Phase 2 trial are to determine the documentary response pace of REOLYSIN(R) in combination with paclitaxel and carboplatin in patients with metastatic or recurrent NSCLC with K-RAS or EGFR-activated tumours, and to measure progression-free survival at 6 months. The secondary objectives are to specify the median survival and duration of progression-free endurance in patients, and to evaluate the safety and tolerability of REOLYSIN(R) in combination with paclitaxel and carboplatin in this patient population.
REOLYSIN(R) preferentially replicates in cancer cells that have an activated RAS pathway. Approximately two thirds of all cancers let an activated RAS pathway, including to the highest degree metastatic disease. A large number of mutations, including mutations in EGFR, Her2 or K-RAS along the RAS pathway lead to RAS pathway activation.
Recent clinical studies in NSCLC with EGFR-based therapies have shown that patients with mutations or overexpression of EGFR, which are usually found in NSCLC, derive clinical benefit from these therapies. An agent such as REOLYSIN(R) that selectively replicates in cancers with an excited RAS pathway resulting from EGFR mutations or overexpression may show similar benefit. However, patients with mutant K-RAS, or up to 20% of the more than than 180,000 patients diagnosed every year in the U.S. with NSCLC, do non derive benefit from EGFR-based therapies. The introduction of screening for K-RAS mutations, and the exclusion of K-RAS mutated patients will lead to higher reply rates in EGFR-mutated or overexpressed patients treated with EGFR- based therapies. This excluded patient group is therefore prescreened for RAS pathway activation resulting from mutations in K-RAS, and an agent such as REOLYSIN(R) crataegus laevigata be indicated for this patient mathematical group. This study targets patients with either EGFR-activated tumours or K-RAS mutations.
"Previous preclinical information indicates that reovirus tends to place in the lungs, and we have seen clinical responses in metastatic lung lesions with REOLYSIN(R) as a monotherapy or in combination with paclitaxel and carboplatin," aforesaid Dr. Brad Thompson, President and CEO of Oncolytics. "A pregnant clinical chance for REOLYSIN(R) is in the treatment of patients with metastatic cancers including NSCLC world Health Organization have a mutated K-RAS gene and are unbelievable to respond to treatment with EGF receptor inhibitors."
About Lung Cancer
Lung cancer is the second near common cancer the Crab in workforce and women and is the leading cause of cancer decease. More people die of lung crab than of colon, breast and prostate gland cancers combined. During 2008, there volition be about 215,020 new cases of lung cancer in the U.S., of which 85% to 90% testament be NSCLC. Only around 15% of people diagnosed with lung cancer ar still alive after phoebe years. There is no single, first-line therapy sanctioned for NSCLC in the U.S., just first-line combination treatments include
Friday, 5 September 2008
Tuesday, 26 August 2008
Do You Have What It Takes To Be The Jonas Brothers Girlfriend?
...more Selena Gomez �
...more The Jonas Brothers �
...more Miley Cyrus �
...more The Jonas Brothers �
...more Miley Cyrus �
Following on from an earlier admittance about their ideal daughter, the Jonas Brothers experience given more details around what they expect from a possible future partner.
The rocker siblings have a wave of eager fans who would love zip more than be wooed by one of the boys, but there ar some requirements which they would bear to match first.
Heartthrob Joe does not want a girlfriend world Health Organization constantly whined. He explains: "If they are shrewish and irritation, you're like, 'Go away'."
Meanwhile, eldest member Kevin doesn�t think he has sentence for a girlfriend. Not even an Italian one?
The 20-year-old says: "We're not ever in truth with people, 'cause we're always travelling. And you get on the earphone and they're like, 'My day is awful, blah,' and you're like, 'This is not what I pauperization right now!'"
However, cutie Nick, who has dated Miley Cyrus and is like a shot romantically coupled to Selena Gomez, has only unmatchable requirement. He lovingly says: "They feature to be good to their moms."
Saturday, 16 August 2008
Risk Of Prostate Cancer After Diagnosis Of Atypical Glands Suspicious For Carcinoma On Saturation And Traditional Biopsies
�UroToday.com - In the September 2008 issue of the Journal of Urology, Dr. Robert Abouassaly and associates from the Cleveland Clinic reported that the finding of atypia on prostate biopsy is associated with a high likeliness of inherent malignancy, regardless of the number of cores taken at the initial biopsy.
The investigators performed this study, because some have suggested that equivocal findings, such as atypia, are due to inadequate prostate sampling at initial biopsy. The chemical group retrospectively determined the peril of prostate gland cancer (CaP) at reiterate biopsy in patients with atypia diagnosed on saturation biopsy. Between 2001 and 2007, a total of 4,139 prostate biopsies were entered into the Cleveland Clinic database, of which 1,068 were saturation. From these, 57 had atypia on initial biopsy and underwent rebiopsy. Nineteen patients had atypia diagnosed on saturation biopsy (20 cores or greater) and 38 had atypia diagnosed victimisation a traditional biopsy proficiency.
Median patient role age was 62 eld, median PSA was 5.0ng/ml, and median time between biopsies was 5 months. Eight of 19 patients (42%) were diagnosed with CaP on replicate biopsy, of whom 7 had Gleason score 6 and 1 had Gleason score 10 CaP. Of the 38 men with atypia on initial biopsy, 15 (39%) had CaP on reprise biopsy. Ten men had Gleason scotch 6, tetrad had Gleason score 7 and 1 had Gleason score 9 CaP. The only divergence between the groups was the men with an initial saturation biopsy were more likely to get concomitant inflaming diagnosed on the initial biopsy. Patients with CaP were less likely to have redness seen at the initial biopsy; only when 5 of 22 work force (23%) with inflammation at initial biopsy had CaP on repeat biopsy compared to 18 of 35 (51%) without inflammation.
These data hint that under-sampling the prostate may not be a factor resulting in the diagnosis of atypia.
Abouassaly R, Tan N, Moussa A, Jones JS
J Urol. 2008 Jul 15. Epub ahead of print.
10.1016/j.juro.2008.05.019
Reported by UroToday.com Contributing Editor Christopher P. Evans, MD, FACS
UroToday - the only urology website with original content written by global urology key view leaders actively engaged in clinical practice.
To access the latest urology news releases from UroToday, go to:
www.urotoday.com
Copyright � 2008 - UroToday
More info
The investigators performed this study, because some have suggested that equivocal findings, such as atypia, are due to inadequate prostate sampling at initial biopsy. The chemical group retrospectively determined the peril of prostate gland cancer (CaP) at reiterate biopsy in patients with atypia diagnosed on saturation biopsy. Between 2001 and 2007, a total of 4,139 prostate biopsies were entered into the Cleveland Clinic database, of which 1,068 were saturation. From these, 57 had atypia on initial biopsy and underwent rebiopsy. Nineteen patients had atypia diagnosed on saturation biopsy (20 cores or greater) and 38 had atypia diagnosed victimisation a traditional biopsy proficiency.
Median patient role age was 62 eld, median PSA was 5.0ng/ml, and median time between biopsies was 5 months. Eight of 19 patients (42%) were diagnosed with CaP on replicate biopsy, of whom 7 had Gleason score 6 and 1 had Gleason score 10 CaP. Of the 38 men with atypia on initial biopsy, 15 (39%) had CaP on reprise biopsy. Ten men had Gleason scotch 6, tetrad had Gleason score 7 and 1 had Gleason score 9 CaP. The only divergence between the groups was the men with an initial saturation biopsy were more likely to get concomitant inflaming diagnosed on the initial biopsy. Patients with CaP were less likely to have redness seen at the initial biopsy; only when 5 of 22 work force (23%) with inflammation at initial biopsy had CaP on repeat biopsy compared to 18 of 35 (51%) without inflammation.
These data hint that under-sampling the prostate may not be a factor resulting in the diagnosis of atypia.
Abouassaly R, Tan N, Moussa A, Jones JS
J Urol. 2008 Jul 15. Epub ahead of print.
10.1016/j.juro.2008.05.019
Reported by UroToday.com Contributing Editor Christopher P. Evans, MD, FACS
UroToday - the only urology website with original content written by global urology key view leaders actively engaged in clinical practice.
To access the latest urology news releases from UroToday, go to:
www.urotoday.com
Copyright � 2008 - UroToday
More info
Thursday, 7 August 2008
The Platters
Artist: The Platters
Genre(s):
Jazz
Discography:
The Original Platters: The Very Best Of
Year: 1987
Tracks: 16
Selection CD 1 of 2
Year:
Tracks: 36
Late-Night Follies
Friday, 27 June 2008
Tuesday, 24 June 2008
Nando Reis Acustico
Artist: Nando Reis Acustico
Genre(s):
Other
Discography:
MTV
Year:
Tracks: 18
Michelle Williams - The Things They Say 8399
Saturday, 14 June 2008
Black Lips, Stephen Malkmus And The Jicks added to Hydro Connect bill
Black Lips, and have been added to the line-up of the forthcoming Hydro Connect festival.
The bash, which also features the likes of Franz Ferdinand, Kasabian and Bloc Party, is set to take place near Argyll, Scotland on August 29-31.
The festival claims to be a committed carbon neutral festival, placing emphasis on being eco-friendly.
To check the availability of Hydro Connect tickets and get all the latest listings, go to NME.COM/GIGS now, or call 0871 230 1094.
The bash, which also features the likes of Franz Ferdinand, Kasabian and Bloc Party, is set to take place near Argyll, Scotland on August 29-31.
The festival claims to be a committed carbon neutral festival, placing emphasis on being eco-friendly.
To check the availability of Hydro Connect tickets and get all the latest listings, go to NME.COM/GIGS now, or call 0871 230 1094.
Sunday, 8 June 2008
Lynda Lemay
Artist: Lynda Lemay
Genre(s):
Pop
Vocal
Rock
Folk
Discography:
Y
Year: 2007
Tracks: 10
Les Secrets des Oiseaux
Year: 2007
Tracks: 15
Un Eternel Hiver
Year: 2006
Tracks: 51
Un Paradis Quelque Part
Year: 2005
Tracks: 16
Autres et videos
Year: 2003
Tracks: 7
Les lettres rouges
Year: 2002
Tracks: 19
Nos Reves
Year: 2001
Tracks: 11
Du Coq A L'ame
Year: 2000
Tracks: 14
Linda Lemay
Year: 1998
Tracks: 11
French-Canadian singer/songwriter Lynda Lemay has been a star in her native Quebec since the early '90s, and besides has a large following in Europe, where her playful, poignant writing style is apprehended for its sympathize with, literate, and much humorous approach to both the large and little requirements of modern-day life. With a novelist's eye for item and an endearing ability to fix light of her own phobias, Lemay writes melodic songs (almost always song in French) that are degenerate comely national treasures in Canada, and her popularity in France stems from her unclutter understanding of the French chanson tradition.
Lemay was born on July 25, 1966, and grew up in Portneuf close the St. Lawrence River outside Quebec City. She showed an early chemical attraction for writing and poetry, and penned her low gear birdsong by the age of baseball club. She erudite to play the guitar in her teens and north Korean won the top spotlight in the Quebec en Chansons Song Competition by the time she was 18. Lemay concentrated on other literary pursuits (including a novel) after graduating from high school, finally reversive to music in the late '80s, presently decent a regular on Quebec's "bars à chansons" circuit. She began to draw label interest after she north Korean won the Best Singer/Songwriter laurels in 1989's Granby Song Contest with her song "La Veilleuse." She released her number 1 album, Nos Reves, in 1991. Her second discharge, Y, featuring medicine arrangements by Marc Perusse, followed in 1994, and was a immense success, finally loss double pt.
Lemay married the Franco-Canadian comedian Patrick Huard in 1995. She toured Europe in 1996 and released an EP of generally live tracks, La Viste, that same year. The button of her third gear album, Lynda Lemay, came in 1998, followed by a uncut live plant in 1999. Du Cog à l'Ame appeared in 2000 and a second live plant, Les Lettres Rouges, came stunned in 2002. A seventh album, Les Secrets stilbesterol Oiseaux, appeared in 2003. Always a versatile writer, Lemay has as well composed a tribe opera, Un Eternel Hiver, which was staged in France in 2005. Un Paradis Quelque Part, her eighth album, was released that same year.
Friday, 6 June 2008
Coldplay Get Overwhelmed By Their Own Song, Pussycat Dolls Perfect Showstopping Act, At MTV Movie Awards Rehearsal
UNIVERSAL CITY, California — You've got to envy the Nick Nolte placard. Not only does it have one of the best seats in the house — right next to Heidi Montag, directly in front of the Pussycat Dolls — but on Saturday (May 31), that simple piece of poster board also got an up-close-and-personal view of performances by both PCD and Coldplay, as the acts rehearsed (and rehearsed ... and rehearsed) their sets for Sunday night's MTV Movie Awards.
On Saturday, the Gibson Amphitheater was a constant whir of stagehands, producers, Steadicam operators, talent wranglers, construction workers, seat fillers and just about anyone you could imagine that would have anything to do with the pulling off of a live awards show. Plus, there was a pair of acts that, combined, have sold more than 13 million copies of their previous albums. And then there's the canned chaos that is the production truck, a mobile TV studio with monitors from wall-to-wall, directors and producers squeezed in, gazing above it all. Everyone's working out the kinks, ironing out the last-minute details, doing things over and over until they're right, all trying to get everything perfect for the big show.
Rehearsal day is remarkable not just for the sheer amount of stuff happening all around you, but also because it's the rare time when some of the biggest acts in the world perform to an audience that either isn't listening (the crew, which is usually checking levels, moving lights or talking on headsets) or isn't real at all (the majority of seats inside the Gibson are taken up by placards — like Mr. Nolte's — which mark where each celeb will be seated during the show). And as such, you get a rather intimate, not to mention fascinating, look at the inner-workings of those acts.
In the case of the Dolls, it's really amazing to watch them work, because of the complexity of their choreography, the synchronicity, the sheer amount of movement they manage in 5-inch heels. And while we can't give too much away, we can safely say that Sunday's performance (of "When I Grow Up," the first single from their upcoming album) is gonna be a doozy, and if rehearsals were any indication, they better be getting hazard pay.
Under the watchful gaze of PCD mastermind Robin Antin and her army of choreographers (not to mention a giant tub of Golden Popcorn located at stage right), the Dolls ascended platforms, descended stairs and ducked walls of flame, all while a massive screen behind them popped with images of flashbulbs, tabloid headlines and diamonds. This went on for nearly two hours, and it didn't always go smoothly. Doll Jessica Sutta (she's the brunette one) was battling a series of blisters so severe that she limped offstage and had a series of padding added to the inside of her heels. Ever the trooper, she managed to gut it out, and by the end of their rehearsals, PCD — plus a group of special guests who we're not allowed to mention just yet — had a fierce and fiery performance locked down.
Meanwhile, the evening's other act, Coldplay, entered the Gibson (cutting quite the unassuming figure for a band that have sold more than 30 million albums worldwide, we might add) and caught the last few minutes of the Dolls' rehearsal. Amazed — and half-joking, we assume — frontman Chris Martin turned to a sea of producers and laughed, "Now I see: You booked us for eye candy."
Fast-forward roughly an hour (rehearsals go very slowly), and Coldplay are standing in the middle of the Gibson stage, a constant wash of stagehands flowing around them, moving amps, setting lights and testing a massive video screen. Perhaps a bit bored (or maybe because he was so impressed by what he saw earlier), Martin wandered over to a keyboard and began plinking out the opening notes to PCD's hit "Don't Cha," then proceeded to warble out the song's hook — "Don't cha wish your girlfriend was hot like me" — to the amazement of pretty much everyone.
A bit later (again, things move slowly), everything was set, and Coldplay launched into "Viva La Vida" — the title track from their new album, which hits stores June 17. Above a massive din of strings, bells and timpani drums, Martin sang about dead kings and failed dreams, skipping about while a Steadicam spun around him. The sheer size of the tune — it's joyously massive, really — was only amplified by the near-empty amphitheater, and as the final notes bounced around the seats and up into the rafters, Martin and the rest of his band stood once again in the middle of the stage, looking a bit shocked. Sunday's show will be the first time they'll play "Viva" live, and you get the feeling that even they were amazed by just how big it sounded.
But then, just as soon as the moment was over, the stage was filled once again with producers and lighting techs, and the whole circus started up again. Sure, that was great, but let's do it again. And again. After all, it's gotta be perfect.
The MTV Movie Awards will air live on MTV on Sunday at 8 p.m. ET! Find all the latest updates on nominees, presenters, performers, voting, contests, movie exclusives and much more at MovieAwards.MTV.com. And check out Movies.MTV.com for the latest movie news, trailers, photos and more!
See Also
Amy Winehouse - Winehouse Sculpture On Display
Troubled singer AMY WINEHOUSE has been immortalised in bronze for an art exhibition in London.
The work, by British artist Guy Portelli, shows the Back To Black singer sitting on a broken champagne bottle, holding a glass and covered in what appears to be pills.
But Portelli insists the work is not a negative representation of Winehouse.
He says, "I would never make a sculpture of someone I didn't respect."
The sculpture is on show at the Mall Galleries in London until 25 May (08).
See Also
Arts diary: Francesca Martin on Simon Armitage's tribute to Paul Weller
Poet Simon Armitage may be among the favourites to be named Poet Laureate later this year, but he has taken time out from such lofty concerns to pen a short story in honour of Paul Weller. The piece - published in the sleeve booklet of Weller's ninth solo studio album, 22 Dreams, which is released this week - follows one man's colourful, dreamlike adventures, which include listening to a busking Noel Gallagher (who himself sings on the album, along with other contributors such as Graham Coxon). Armitage wrote it as an interpretation of the story he feels the album tells. A long-term Weller fan, Armitage has previously praised another of Weller's songs, Thick as Thieves, for its "terrific standard of writing", adding that it summed up the fact "that you have to leave your past behind if you want to learn and develop and grow as a person".
· Email your arts stories to arts.diary@guardian.co.uk
See Also
Ottmar Liebert + Luna Negra
Artist: Ottmar Liebert + Luna Negra
Genre(s):
New Age
Discography:
La Semana
Year: 2004
Tracks: 12
Grey's Anatomy star Chambers hospitalised
Mom & Pop Get the Led Out
BOSTON, June 2 -- It's the same old story. Boy meets girl.
Boy and girl fall in love. Boy and girl get married, start a design
company, name it Got Your Nose, and -- before you know it -- build a
website for Led Zeppelin.
It's all part of the new paradigm shift that's giving those with the
right skills the ability to weather this troubled economy and the freedom
to work not just from home, but from virtually anywhere. Got Your Nose
co-founders Raegan McCain and Steve Brykman are two such people.
"When we left L.A. in 2005 and moved back to Boston to raise a family,
none of our clients batted an eye," says Raegan. "We kept all our Hollywood
contacts and don't have to deal with smog or traffic anymore."
But this isn't just any mom & pop pair. There's a reason Warner
Brothers and Twentieth Century Fox still look to them for online movie
campaigns. These two know what works. They've been in the Internet game
long before Amazon made its first sale, back when people were mesmerized by
blinking text.
As an award-winning writer and former Managing Editor of National
Lampoon, Steve is no stranger to off-beat marketing. You may have seen him
on G4TV touting his "impeachment beard" or in the New Yorker, after he
posted the Lampoon writing team for sale on eBay.
Raegan shapes the creative strategy of all G.Y.N. projects. An award
winner for her work with AFI and Transamerica, before Got Your Nose, she
art directed projects for Sony, Universal, and was instrumental in creating
Honda Financial Services' online presence.
"Let me put it this way," her husband brags, "When American Honda
needed someone to redesign their eStore to fix usability issues causing
flagging sales, they called Raegan."
So when Warner Brothers asked them to build a website for the new Led
Zeppelin Song Remains the Same DVD, they were ready to rock. And no wonder.
They're the best of a new breed, proving it's still possible to have it
all.
The only thing you're probably wondering is: How do they manage to work
together 24/7 and remain happily married?
"It's simple," Raegan says. "Respect. While we brainstorm ideas
together, we have very distinct roles. Plus, a talented team of contractors
keeps us both from going crazy."
What's next for Got Your Nose? These days, they're thinking of creating
the ultimate working vacation, touring the country in their Westy, taking
their business (and their daughter) on the road.
Oh, and about that name ...
"We wanted to stand out among the sea of cyber-somethings," says Steve.
"Besides, once you hear Got Your Nose, you never forget it. It says, 'We
don't take ourselves too seriously. We're fun to work with. So go ahead and
give us a call.'"
To reach Raegan & Steve, or to view their work, visit
http://www.gotyournose.com.
Media contact:
Steve Brykman
781.729.2773
brykman@gotyournose.com
This release was issued through eReleases (TM). For more information,
visit http://www.ereleases.com.
See Also
Boy and girl fall in love. Boy and girl get married, start a design
company, name it Got Your Nose, and -- before you know it -- build a
website for Led Zeppelin.
It's all part of the new paradigm shift that's giving those with the
right skills the ability to weather this troubled economy and the freedom
to work not just from home, but from virtually anywhere. Got Your Nose
co-founders Raegan McCain and Steve Brykman are two such people.
"When we left L.A. in 2005 and moved back to Boston to raise a family,
none of our clients batted an eye," says Raegan. "We kept all our Hollywood
contacts and don't have to deal with smog or traffic anymore."
But this isn't just any mom & pop pair. There's a reason Warner
Brothers and Twentieth Century Fox still look to them for online movie
campaigns. These two know what works. They've been in the Internet game
long before Amazon made its first sale, back when people were mesmerized by
blinking text.
As an award-winning writer and former Managing Editor of National
Lampoon, Steve is no stranger to off-beat marketing. You may have seen him
on G4TV touting his "impeachment beard" or in the New Yorker, after he
posted the Lampoon writing team for sale on eBay.
Raegan shapes the creative strategy of all G.Y.N. projects. An award
winner for her work with AFI and Transamerica, before Got Your Nose, she
art directed projects for Sony, Universal, and was instrumental in creating
Honda Financial Services' online presence.
"Let me put it this way," her husband brags, "When American Honda
needed someone to redesign their eStore to fix usability issues causing
flagging sales, they called Raegan."
So when Warner Brothers asked them to build a website for the new Led
Zeppelin Song Remains the Same DVD, they were ready to rock. And no wonder.
They're the best of a new breed, proving it's still possible to have it
all.
The only thing you're probably wondering is: How do they manage to work
together 24/7 and remain happily married?
"It's simple," Raegan says. "Respect. While we brainstorm ideas
together, we have very distinct roles. Plus, a talented team of contractors
keeps us both from going crazy."
What's next for Got Your Nose? These days, they're thinking of creating
the ultimate working vacation, touring the country in their Westy, taking
their business (and their daughter) on the road.
Oh, and about that name ...
"We wanted to stand out among the sea of cyber-somethings," says Steve.
"Besides, once you hear Got Your Nose, you never forget it. It says, 'We
don't take ourselves too seriously. We're fun to work with. So go ahead and
give us a call.'"
To reach Raegan & Steve, or to view their work, visit
http://www.gotyournose.com.
Media contact:
Steve Brykman
781.729.2773
brykman@gotyournose.com
This release was issued through eReleases (TM). For more information,
visit http://www.ereleases.com.
See Also
Steve-O pleads guilty to drug offence
Jackass star Steve-O has pleaded guilty to cocaine possession and will have to attend rehab for two years.
The deal will mean the stunt-man will not have to go to prison.Steve-O, real name Steven Glover, was arrested in March over an argument with a neighbour about a fence, after which police were called. Drugs were subsequently found to be on his person.
His lawyer Barry Gerald Sands said: "Steve is doing great - he has been sober for 85 days. His probation is set for 18 months, but it may be shorter depending on his good behavior and continuation with the program he is in. He is a model individual. He has changed completely. He is a sober man."
Steve-O, 33, recently checked into the Cedars-Sinai Medical Center and revealed in a blog post that his Jackass co-star Johnny Knoxville "came to my home" and "forced me into the hospital".
The deal will mean the stunt-man will not have to go to prison.Steve-O, real name Steven Glover, was arrested in March over an argument with a neighbour about a fence, after which police were called. Drugs were subsequently found to be on his person.
His lawyer Barry Gerald Sands said: "Steve is doing great - he has been sober for 85 days. His probation is set for 18 months, but it may be shorter depending on his good behavior and continuation with the program he is in. He is a model individual. He has changed completely. He is a sober man."
Steve-O, 33, recently checked into the Cedars-Sinai Medical Center and revealed in a blog post that his Jackass co-star Johnny Knoxville "came to my home" and "forced me into the hospital".
Panic At The Disco Measure Their Success With Live Shows: 'You Can't Download The Concert Ticket'
Now that they're done with the online puzzles and have successfully weathered the storm of punctuation-gate, Panic at the Disco are finally getting down to the business of being a band.
Or, more specifically, a band on the road, promoting their second album and trying to convince the naysayers that they're more than just a flash in the pan. Which is why, in their current headlining slot on the Honda Civic Tour, they've ditched the 10-ring circus that accompanied them on their last jaunt, replacing all that ephemera with a stripped-down, focused set that showcases the music and not, say, the contortionist mimes.
So how's business been? Well, it sort of depends on how you look at things. Because while that second album, Pretty. Odd., has garnered positive reviews, it's yet to really catch on with consumers (it debuted at #2 on the Billboard albums chart back in March but has currently sold less than 250,000 copies). And while most bands might be all doomy and gloomy about those numbers, Panic are more content to focus on more tangible (and, some might argue, accurate) ways of measuring success.
"It's really strange. Even on the last album, it didn't come out of the gates and have success, but there were weeks where we'd sell 50,000 records, and the album had been out for almost a year," guitarist Ryan Ross said. "And that kind of stuff doesn't seem to happen anymore, so it's really hard to judge how the album is doing based on record sales, you know? We look at that, and we don't really know what that even means. All we can go off is being on this tour and seeing that people are getting into the new stuff, and that's the only way we can tell firsthand if things are going well or not."
"It's a really weird time for music and it's hard to tell where you stand, and all the things that used to tell you about your band have kind of gone away. So how you perceive yourself has changed," drummer Spencer Smith added. "Luckily for us, rock bands have always been about playing live, [which is] good for us, because we're a real band who plays our own instruments, so we love being able to do it. And luckily that's always going to be there, because you can't download the concert ticket."
And while Odd.'s reception has forced Panic to rethink the concept of success, the record has also put them in some rather unfamiliar territory: They've become (sorta) elder statesmen in the Fueled By Ramen/ Decaydance/ Pete Wentz universe that has dominated the rock scene for nearly three years now. And as such, they've begun to enjoy the perks of life as a big-time rock act ... on a decidedly Fueled By Ramen/ Decaydance/ Pete Wentz budget, that is.
"We've got some flowers onstage now — they're fake though," Smith laughed. "They have to be, because a month into the tour, they probably would've gotten shredded up."
"We had an idea to get a tour plant to take care of, in that whole spirit, but we have yet to do that," bassist Jon Walker added. "You know, maybe a fern or something. A ficus."
See Also
Navajo
Artist: Navajo
Genre(s):
Electronic
Discography:
Chants
Year:
Tracks: 11
Hailing from the metropolis of Puerto de Tuxpan de R. Cano in Veracruz, Mexico, the Latin pop sextet Navajo comprised isaac Bashevis Singer Miriam Villalobos, accordionist Hector Murrieta, guitar player Miguel A. Galindo, melodious film director and bassist Francisco J. Galindo, drummer Ignacio Lozano and percussionist Hector. Formed in 1984 as accompanists for a 350-person vocal choir, the grouping broke through to a national hearing three long time later, when they were among the upside finishers in the esteemed OTI Music Festival; extensive touring followed, and in 1998 Navajo made their American debut with the album Celos.
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